Statins Updated

A poster posited a link between Parkinson's Disease (PD) and Statin use, which led me to an article in Movement Disorders, 2006 (PubMed ID 17177184) that points out, in a retrospective study, a strong link between low LDL and Parkinson's incidence. The lower the LDL, the more people had PD: up to 3 times as often with an LDL below 93.

However, that same article seemed to find a 'neuroprotective' effect for statins. The poster obviously knew more biochemistry than me, so I'm not incredulous, that's just what I found in an admittedly quick search. Updated articles are welcome. It certainly did confirm a link between low LDL and Parkinson's, from which I can infer that LDL is perhaps not entirely deserving of the pejorative 'bad' cholesterol label.

A Google search on statins, however, on the broader issue of Number Needed to Treat analysis, showed very high NNTs, like 33 here, based on a 2003 Lancet article. I'm not sure how reliable that is. However, with an NNT of 33 in people with diabetes, I suppose there is good reason to question statin use given the lack of mortality benefit, and given the serious side-effects; I'm not sure about PD, but pancreatitis and rhabdomyolysis are no picnic.

Just don't ask what the NNT is for epinephrine in out-of-hospital resuscitation. The evidence for a lot of our critical situation algorithms seems a bit thin from podcasts I listen to. Just a tad bit hard to study.


The Cholesterol Controversy, or Are We Getting Fleeced by Statins?

5 billion a year, according to this wellness site that I found with a Google search, is how much the big drug companies are fleecing the public for. A lot of this flap came from the 'failed' Vytorin study, which is unpublished but findable in the Medical Letter here, and in a statement from the American College of Cardiology here.

The study was a randomized trial of people with Familial Hypercholesterolemia and showed no difference--actually, Vytorin was less effective than simvastatin--in slowing the growth of plaque. Forbes said their stock tanked. The wellness site above points to it as evidence that lowering cholesterol is a farce (and, of course, we should buy his book).

The Health Beat blog, which I like but which appears to have a bias against pharma, takes on the topic here. For a bit, I felt betrayed. Here I had been talking to people about lowering their LDL and treating cholesterol for weeks, and the dogma is that statins as a class are being used more and more, not less.

We've been looking at pictures like those at right for years of medical school, learning how to treat it with drugs. Don't they work? Well, actually, yes. Let's talk about endpoints. There is a big study in the Lancet in 2008 (PubMed ID 18191683 at pubmed.gov) that was a meta-analysis of 18,686 diabetics which supported a reduction of 1/3 in major vascular events.

A 2006 study in the Archives of Internal Medicine (PubMed ID 17130382) showed a reduction in major vascular events with NO reduction in all-cause mortality. There was, of note, a 14% reduction in the incidence of stroke.

Critics, including Health Beat, argue that lowering LDL numbers do not affect all-cause mortality and therefore are not useful as there is no quantifiable evidence that quality of life goes up, and there are side effects to statins. True. Also, the Lancet article in particular is a meta-analysis of industry-funded studies, which it admits.

Still, large meta-analyses are about as trustworthy as evidence-based medicine gets, and many drug studies are industry funded.

Are statins a fraud? Just money? A plot by Big Pharma to fleece us of billions?

Of course Big Pharma wants to make money, and tons of it. It is the fundamental mission of private companies to make lots of money and they should. No one should have any illusions about that. This perhaps goes towards why we should have a public health care system. But I digress. The question is if people were fleeced, should ask for their money back, were betrayed, and so on. The wellness sites and others point out that lowering cholesterol naturally with diet and exercise is a better way to do it and statins are a rip-off.

Guess what? We tell our patients that. We say, you should lose weight, eat right, and exercise. A lot. Now. And how many do? In six weeks of primary care, I saw TWO people who had done that. They were healthy, happy, had great numbers and a very high quality of life. We encouraged them, held them up as examples. TWO of them.

So should we avoid treating with statins? If I have a person who, for whatever reason (perhaps because they're a tad lazy) can't lose weight, watch their saturated fat intake, or exercise, should I tell them to just go away? Umm...no. Should I avoid giving an elderly, male, smoking, diabetic a drug that might reduce his chances of having a stroke because he SHOULD quit, eat greens, and run a marathon? No. I'll tell him that every visit. But guess what? He just might not listen.

We should accurately represent what statins do: they make a noticeable difference in the risk of a cardiovascular event, but it is mild. It's not a miracle cure. You should stop if you get muscle aches and so on.

But call them a con and a fleece? Western medicine has said all along that patients should eat right, exercise a lot, not smoke, lower their stress level, and so on. It's easy to jump on the statin 'push' and say doctors and the medical establishment are just in it for the cash, because it absolves all those sedentary junk-food eating patients of any responsibility for their terrible disease burden. As an added side bonus, it often helps sell diet books and alternative medicine, which as far as I know, doesn't come with a money-back guarantee, either. Far from it.

OF COURSE Big Pharma wants to make money. Most doctors (I admit, not all) want to help patients. And we figure that even those people who choose not to modify their lifestyle deserve some recourse to try and prevent badness. Crazy us.

To close the circle, let's go back to the Vytorin study. The drug failed to beat simvastatin with regards to thickness of plaque in people with FH, a rare genetic disorder. So, the endpoint doesn't matter (mortality, heart attacks, and strokes matter) and the population is not applicable to every patient. Is it disappointing? Sure. Does it mean statins don't do anything? No. Patients and doctors shouldn't rely on them to get them out of the work of modifying behavior.

There is no quick fix.


Yay! Accepted!

To something, at least...the HealthCare blogger Code of Ethics. Click on the badge to the right to see what they are about. Voluntary oaths are important because they represent our desire to police ourselves and present an ethical standard to any readers who happen to wander by (perhaps not that many, but who knows?)


No Hay Disculpas Por El Uso Excesivo!

"There aren't excuses for excessive use". So says the poster about antibiotic use. Shouldn't that be directed at physicians? Aren't we the ones who hold the power to give, or not, that overestimated, well-named Z-pak for sinusitis?

Just the other day a father came in with what sounded like a nasty sinus infection, daughter in tow, 6-month pregnant wife at home, and asked for something to 'wipe out' the nastiness in his head so he could take care of his family. Noble. Hard to refuse. It's not for his gain. The enemy is easy to visualize--the enemy is snot.

It's not, because the enemy is resistance, the best argument yet against the creationists that evolution, despite their protests about intelligent design, is real and happens constantly.

Is there evidence to support giving antibiotics? The studies are numerous. A British Medical Journal article in 2003 found no difference between placebo and Augmentin (amoxicillin plus an augmenting agent) in clinical cure rate, and the patients were selected with 'pus on rhinoscopy' which is how we often do it in the office, rather than x-ray or aspiration (needles into your sinuses). The Cochrane database, a respected organization that collates results, found at best moderate improvement and recommended amoxicillin. The British Medical Journal also has a 'Clinical Evidence' site that summarizes articles they found through 2004 that show no significant difference between treated and untreated patients given placebos in symptoms. So even if we think it will make our patients feel better, it won't, and according to the website, no surprise, there is a significant increase in diarrhea.

Of course, there are other reasons to avoid treating patients. MRSA, on the left, is increasing. A recent Emergency Medicine symposium sponsored by the University of Kentucky (as well as Ortho-McNeil) on CA-MRSA has some interesting points. Penicillin (a relative of amoxicillin, what we typically use for sinus infections) was first introduced in 1941. Resistant S. aureus, the SA in MRSA, was first reported in 1942. Isolated reports of community-acquired MRSA started in the 1980s. A Detroit outbreak in the 1980s showed an increase of resistance from 3% to 38% in only 19 months. In LA, one ED saw MRSA rates increase from 29% to 64% in 3 years. Across the country, an average of 59% of all soft tissue infections presenting to the ED are MRSA.

So what, you might say. What does this have to do with me wanting my Z-pak so I feel better the day after I get sick? Well, how are these increases occurring? We know MRSA is spread by contact, so maybe all these people are really close. Or...surveillance testing of MRSA is conducted by swabbing someone's nostril, where the MRSA lives when it's not invading the lungs or skin or CSF. As seen by the 1941-1942 time gap, penicillin and related antibiotics induce resistance. And we see a quick increase in communities. MRSA lives in the nose, and sinusitis is in the nose, too! So we know we're putting antibiotic pressure on a patient's upper airway.

How much is antibiotic pressure contributing to the rise of MRSA strains? If we give that person with acute sinusitis amoxicillin, are we contributing to the rise of MRSA? I haven't seen a study that documents one way or the other in specific patients with sinusitis, but overall misuse of antibiotics leads to resistance. This article breaks down the major primary care complaints--ear infections, sore throats, and sinus infections--as they relate to resistance.

It gets worse. The same article estimates that up to 10% of CA-MRSA infections are invasive. Osteomyelitis (bone infections, nasty) and pneumonia are being seen in previously healthy patients, and they seem, for whatever reason, to be in young patients. Mortality for CA-MRSA pneumonia ranges from 25-60%, according to the symposium mentioned above.

So there are good reasons not to treat. In the nice clean office with a person snuffling miserably imploring you for antibiotics, who has been told by all their friends that all they need is a Z-pak to 'nip that thing in the bud', it's hard to hold the line. I heard a story the other night of one parent telling another to go get a burst of prednisone, really strong medicine with significant side effects, for their kid's cough. Not trouble breathing or major asthma exacerbation, their cough. But what's our job? To make people comfortable? Sometimes. But we can do that with supportive care and empathy. Our other job is to try and prevent them from dying or being sick for the rest of their lives. For that part of our job, we should send them home most, if not all of the time, or at least until they've had 7 or more days of serious symptoms.


Moral Obfuscation

I said below in the Cat Scratch Fever post that I would return to the act of moral 'obfuscation' when a patient didn't have a complicated, Zebra-like diagnosis but rather a common one.

Obfuscation isn't the right word. More like moral ambiguity. As famously defined in the movie Girl, Interrupted, ambivalence means being pulled in two directions. This happens more with dramatic cases and sick patients than with routine visits.

As medical students we're all pulled in two directions when people are really sick. On the one hand, I feel bad for them and hope they are well. On the other hand, which is not exactly the opposite direction, I am often excited with dramatic cases because I get to do something exciting. Then I feel bad. Then I realize that this curiosity leads to learning which benefits patients. Then I feel bad again.

It's the ambiguity of feeling you are in the right place at the right time and have a purpose in life, and that time and place is not a happy place. At least for others.

Are We Really This Upset About Vaccines? Part 1

I've seldom seen a medical issue that polarizes so completely as immunizations do. Advocates seem to veer easily off the highway of reason into the canyon of hyperbole.
Of course, I want to write about it. Wikipedia has a good background article on the Thimerosal controversy here, and thimerosal itself here. They also have articles on all the immunizations discussed here.

Certain subsets of people seem to think that there is nothing short of a global conspiracy to cover up the 'fact' that autism is caused by vaccines--probably the same people that shot JFK, tried to take over the US with black helicopters in the nineties, and are still witholding information about Area 51. Sorry, I had to poke a little fun.

As personal background: I believe in immunizations. Our children are immunized. With that said, we asked for thimerosal-free vaccinations, and we postponed certain vaccines. I see no reason, for example, that I, as a careful parent who attends pediatric visits, need to get my child vaccinated with Hepatitis B vaccine (a disease that is transmitted either by sexual contact or blood and body fluid exposure) on the day of birth. All our decisions to postpone and then complete vaccines were done with the assent of our pediatrician. I've never had an argument from them about postponing certain vaccines.

I recently received an e-mail about a website, Generation Rescue, that contends two main things: autism is reversible, and vaccines caused its rise. They have recently taken out ads in USA Today and the New York Times, among other outlets, contending that we are over-vaccinating our children, and this has led to autism increase, and it's being covered up. Both Don Imus and Robert F. Kennedy, Jr., have lined up along similar lines. They are mentioned on the above website.

I'm not on any sort of a smear campaign; I should say that it seems perfectly reasonable to remove thimerosal, a mercury-based preservative, from vaccines (which is why it's already been done for the most part). I also think that most of the therapies they list on their website for children likely do a lot of good--detoxification, correction of vitamin deficiencies, complementary medicine, and so on. They are also justified in sounding the alarm about the rise in autism, which is alarming. However. I do have a teeny-weeny bone to pick with them.

In part 1, I'll look at their specific ad, and say outright that it's misleading. They point to the increase in shots recommended by the CDC from 10 in 1983 to 36 in 2008. They then quote autism rates in 1983 as 1 in 10,000, rising to 1 in 150 in 2008. The ad is in PDF form here.

OK, let's be rational. First, are their incidence rates correct for autism or ASD (autistic spectrum disorders)? The 1 in 150 number looks accurate even according to the conspiratory and shady CDC (sarcasm intended, sorry, I'll try and keep it down) as seen here. However, they state that this incidence number has been relatively stable since 2000 or so, which will be important later on. What about the 1 in 10,000 number? A Google search reveals this article, which has an incidence of 5.5 per 100,000 in 1976, or 1 in 20,000 in Olmstead County, Minnesota. A couple other Google searches showed similar numbers; I don't see a footnote for the statistic, but it seems reasonable based on the above article. Overall, they have a point; there has been a rise in ASD prevelance (the total number of children affected by the disorder at any one time).

Now, how about the syringes portraying the number of vaccination recommendations and the 260% increase? Again, overall, they have a point that there are more shots recommended now as compared to 1983. However, there are some very important points to be made.

Point 1: MMR is present both in 1983 and 2008. It's not hard to do a web search and find supposed links between the MMR vaccine and autism. 60 minutes has done a piece on it. So, if the rate is rising, how could MMR be linked if it hasn't changed?

Point 2: along the same lines, rotavirus accounts for 3 of the 36 total 'shots', and varicella accounts for 2. Rotavirus was only just approved for use. Most importantly, though, rotavirus vaccine, a.k.a. Rotateq, is an oral vaccine, not a shot. The website makes the accurate point that injecting vaccines bypasses metabolism in the liver, but Rotateq does not and shouldn't therefore be in the list. 33. Varicella, or chicken pox, was only changed to be recommended in a two shot series in the last year or so, so recently that the CDC and state health departments aren't tracking adherence to the two shot regimen closely to monitor up-to-date rates. Both of these recommendations are so recent that there's no way they could contribute to the rise in autism, either. The same is possibly applicable to Hepatitis A, for which the recommendations are changing dramatically and often. It was only recently added to the general schedule.

Point 3: The 1983 schedule included the old version of pertussis (Whooping Cough). Interestingly enough, this vaccine was resisted because there were many reports of brain damage unproven by studies at the time, according to the Wikipedia article above, not dissimilar to the current controversy. That vaccine was replaced in 1992, meaning that the 2008 series is safer with regards to the new pertussis vaccine, which is not a live virus.

Point 4: The 1983 schedule contained the oral polio vaccine, which was likewise discontinued in the US and replaced in 1987 by a newer version of the inactivated polio vaccine. Why? It was thought to be contaminated by simian virus 40, linked to cancer but never proven. Again, the new schedule is safer.

Point 5: Seldom are children up to date on all of the vaccines listed. The CDC measures vaccine coverage with a so-called 4:3:1:3:3:1 count, for DTaP, Polio, MMR, Hib, HepB, and Varicella. As shown by this map, coverage is above 80% in only 12 of 50 states, and below 69% in 6. Vaccines such as Hepatitis A, the second Varicella booster, rotavirus, and Prevnar are not even counted because they were introduced or changed more recently, and it takes time for these changes to take effect.
Why do these matter? I'll discuss more in future installments on causation versus correlation and therapy. But these inconsitenciesand biases in the advertisement make me wonder about the conclusions. Does it seem reasonable to avoid mercury in vaccines? Yes (which is why the AAP advocated it years ago, discussed soon). Does it seem possibly reasonable to modify the vaccine schedule? Sure. Is it alarming that autism has risen? Yes (I'll talk more about that, too).
Is all this due to vaccines? Is it worth demonizing vaccines in a full-page advertisement? Is it worth returning to 'nature', so to speak, and letting Haemophilis Influenza, chicken pox, diptheria, tetanus, pertussis, influenza, streptococcus pneumoniae achieve whatever infection rates they would with no immunization?
It's easy to see that I think the answer to those last questions is an emphatic no.


I Wish It Were Cat Scratch Fever

A tale of black cats and clear vodka in multiple acts. The chief complaint is a cat bite. I go in to talk to the patient, and sure enough, she has a tiny cat bite on her shin that looks to be healing well, but is exquisitely tender along the tibia and up around the knee.

Cat bites are a favorite of medical students because they can cause Cat Scratch Fever due to Bartonella henselae; one of the cooler diseases by name and because there's a Ted Nugent song named after it. Short of that disease, cat bites are notorious for causing infection because, as one attending put it, 'their teeth are like hypodermic needles for injecting bacteria'. One more reason cats are cute...from afar. I'll stick with Golden Retrievers, thanks.

The patient is dressed in jeans, hiking boots, an old sweater. She has a calligraphic tattoo on her neck. Any other symptoms? Speech is slurred. Well, diarrhea, she says. Green, the color of the paint on the wall (no, we don't have poop colored walls. Kelly green). And I throw up like clockwork every day at 5 or 6 am, and again at 7 am, so I can't take my medicines.

Were you sick before you had the cat bite? Well, yes. Part of me is disapointed, in a fit of moral obfuscation I'll talk about in a later post. No Cat Scratch Fever. But she has had fevers, and chills. And abdominal pain. And shortness of breath. Her exam reveals lungs that sound like a hyperactive gnome playing with tin foil. Her abdominal exam shows marked guarding (muscles tense with any pushing) under the ribs on the right and just below the bottom edge of her sternum.

Sometimes I go into a room without reading the chart a lot in order to simulate my future life with its total lack of any sort of continuity with the exception of drug seekers and cold homeless people.

So, I was thinking, gosh, could this be pancreatitis? Ulcer? Sepsis secondary to the cat bite was unlikely, no matter how much I wanted the cat bite to be something interesting.

To be safe, I read the chart. She had presented with exactly the same thing, minus the cat bite, three weeks ago, and again before that, so on and so on for years. Further questioning revealed that she had also been drinking a liter of Vodka, again. She has had elevated lipase levels and acute pancreatic attacks before. Probably was pancreatitis again. But it wasn't from the cat. The poor cat bit her because she was ataxic from the vodka and about to step on her kittens. And, oh yeah, the meds she couldn't take were psych meds.

My first car was a 1974 Volvo station wagon that couldn't get over 50 MPH even on a downhill, but somehow managed to keep running for years. Every once and a while I would change a hose, change the oil, get in a fender bender, have a friend jump on the roof at a party and dent it irreparably. The steering wheel lost it's cover one day. It just fell off. But eventually we sold it, still running. I saw it one day downtown, still going.

Some patients are like that. I can't for the life of me figure out how they keep going, but they do, with their panaloply of ailments, dragging through life. I haven't solved them yet. I wonder if I will. Until then, it'll be easy to form compassion for them. I used to love that old car too, even when it didn't work so well.


The Candidates on Health Care

Let's hope these two pictures don't start fighting.

I've learned some interesting things from the health care plans of each candidate, Hillary's and Barack's. Also discussed by Paul Krugman of the NY Times here.

Here's my favorite. According to Hillary's fact sheet, the average yearly health insurance premium for a family in 2006 was $11,480. Eleven thousand dollars! That's more than it costs to mortgage a house (well, a small one at least). In effect, every family in the US owns a second home--their clinic.

Is there a big difference between the two plans? Well, both mention creating something similar to congress's plan, the FEHBP. Both want to increase coverage of kids especially. Neither is advocating a true single-payer system. Both want to 'increase competition' between health insurance providers, whatever that means. Both want to replace Medicare's ability to get discounts from drug companies based on size, removed during the Bush administration. Both stress preventative health regimens and incentives for 'quality'. Both discuss electronic medical records. Otherwise, they seem similar with the exception of some differences below. In general, Hillary's plan seems much more detailed, with more references and more numbers. They kind of fit the personalities of the candidates.

Hillary plans $3 billion a year for implementation of electronic medical records, Barack $10 billion. I suppose that doesn't matter since Hillary pegs savings from EMR implementation at $77 billion a year, once up and running.

Barack mentions a new 'National Health Insurance Exchange' that will increase competition, but I'm not sure how. Hillary doesn't really address competition between health insurance companies, but does talk about restoring discounts.

Hillary talks about 'sensible' malpractice reform, basically a system by which doctors are held to 'transparent' standards with regards to error rates. Barack doesn't really talk about malpractice reform. This is a big issue in some states where caps on damage awards have recently been rescinded. I'm not totally sure it's a good idea to measure MDs on quality while ignoring the price-cap issue and the sheer cost of malpractice insurance in many states.

Hillary talks about a national research initiative to find best practices. A new 'Institute'. That sounds nice, I suppose.

Krugman and others believe that Hillary's plan will lead to universal coverage, through mandates that require people to buy coverage. But neither plan says anything about what 'affordable' or 'reasonable cost' means. Barack's plan pledges universal coverage for children, but leaves out those who don't want to buy coverage. Doesn't that leave them back at the ER again? Aren't those the very catastrophic injuries that cost so much?

In reality, there's no great way to compare these because they're both simplified and hypothetical.

The bottom line, for me? If there were a single-payer system, there would only be one place to send a bill, one place to worry about funding, and one place that, if federal, would be required by law to disclose where all the money goes. Don't we want that? Don't we think that if we spend trillions on health care we'll be able to pay our doctors, create short wait times, and still do research?

I guess in the end I don't see the appeal of the system we have now such that we aren't talking about a single-payer system. Yes, Hillary's plan seems a bit tougher. But both are incremental change to a broken system. Good luck with that, says my cynical side. Is there a better way, asks my pragmatic side. Maybe not.

Single-Payer Healthcare

There's a great entry here on the Canadian health care system from the Health Beat Blog, which seems apropos given our current political chance to perhaps make some changes.

I'm no policy expert. But I do know my own finances. In our wonderful system that operates in a free market, this is what happened to me as a father of one to three children, depending on when it happened.

When I had employer-based insurance, as is typical, I had to pay a premium for my family of between $200 and $300 a month. I couldn't switch plans once I had chosen one even though I wanted to--so much for free choice of doctors. Once I became a student, I had to either sign up for student health--over $500 a month with lots of co-pays--or use COBRA, an obscure system whereby the newly unemployed person pays the 'full' cost of their insurance which in my case was $575 a month but at least I had the same doctor.

I was unemployed, paying $575 a month. Awesome. This is the system we currently have. Lost your job? Here's an extra $500 a month in expenses.

18 months later, we were eligible for Medicare. Cost: $0. Choice of doctors: well, pretty much any. In fact, my access to academic providers went up substantially, and I didn't need prior authorization. Wait times were similar. I got to keep the same pediatrician for my kids and choose pretty much anyone for my own primary.

Advantage, big bad government system. In both choice and cost.

But surely, doctors are paid better in the US? So you wouldn't want a government system? Well, I currently have $175,000 in loans from medical school. Partially because there were no social services whatsoever, so I had to borrow money to pay for health insurance. EVEN WHEN I'M WORKING the cost of health care per month will rise again to between $150 and $500 a month depending on where I work (let's say the American South is not 'service rich'). Do I want a good salary? Sure, but only because I have so many loans because I had to finance both my own education and pay exorbitant premiums for health care (under COBRA, above) while I was a student.

Is there any hope? There is one notable institution that supplies free health and dental care to all its employees. What? A medical institution that gives free health care to all its employees? They must be going bankrupt! No, actually. They thought about going to a plan before. Just playing for care without the administrative cost was...cheaper. Golly.

Pretty obvious to me. Government plan: free, better access. Employer plan: expensive, less choice. And that's even without any static for prior conditions and all that garbage, or mental health which is not always covered, and so on.

Oh, right, taxes. Well, let's see. Taxes might be higher with more services, it's true. From where I'm standing, however, government health care saved me on average $500 a month. That's $6,000 a year. Now, I'm no expert on taxes. But according to Wikipedia on taxation (granted they may have a bias) that's more than a person making $40,000 a year will pay for their TOTAL tax bill. So for me, going to a government plan actually more than paid for my taxes the years I was eligible. In other words--government health care helped my true out of pocket expenses go down, not up.

I don't know if this convinces you. It does me. Leave aside the small observation that all other developed nations have universal coverage, and that the nations with the largest tax burden and therefore, the largest support network also have the best social indices: that fabled land, Scandinavia.

Best Emergency Medicine Podcasts

In order to survive medical school and residency with children, I've had to be creative, and one of those 'creative' ways of stuffing tidbits like appropriate discordance in a LBBB into my head is through podcasts.

Of course, then my iPod cord gets stuck on the baby seat and so on. But I digress. Here are my picks for the best EM Podcasts, all available through iTunes.

1. University of Iowa Emergency Medicine Podcast. This is a mix of audio and video aimed at both EM MDs and EMS EMTs. Video podcasts are procedural and typically short; I could do with some more explanation but overall these are really interesting.

2. Albany Medical Center EM Podcast, link supplied by podanza.com which I have no knowledge of. Albany also has a series for EMS, These audio EM podcasts are very dense and have great content, especially their EKG lectures.

3. ACEP 'Focus On' Series. The link here is to the ACEP website and the text version, but this is also available through iTunes. These are shorter, usually 15 to 20 minutes, and professionally done by an announcer. I have to give a shout out to Dr. Lutes at MCW as he has two episodes to his credit, and I loved my rotation in Milwaukee and working with him.

There are lots of other podcasts out there, but for my time, the three here are by far the most weighty and the most EM specific.


You're Fine, Go Home

Ah, clinic.

Not the ED. Being in clinic makes me respect the family practitioner. Most of the time they are given 15 to 20 minutes total, even at an academic clinic, and 10 of that gets eaten up by the nurse rooming the patient. Once they enter, they have to (and often want to) receive an update on the rest of the family.

And then they have to proceed with the sorting. Sort the lipids, sort the glucose readings, sort the thyroid hormone levels, and sort the day-in day-out wheat from the dying chaff.

Because it's very possible to miss someone sick. In the ED, at least we have the luxury of saying, 'what esoteric disease might kill this patient soon?' and then doing our work-up within the next hour for that. But in the clinic, any test takes time, most people aren't sick, and the pressure is to move them out. Improve their lipids, improve their BP.
But don't miss. To actually tell someone, 'go home, you're fine' after you've considered with a fair amount of energy all the terrible things that can happen to them is more difficult. You find yourself wondering what's in their CSF--is it meningitis (Neisseria meningitidis, as above)? Can you rule it out on history alone?

The studies say yes, sometimes. The studies say you can irrigate lacerations with tap water. But it's different to be confident enough to do it. One girl recently, 11, good in school, came in to make sure she didn't have meningitis as her mother had been admitted the other day. My thin-slice thought (immediate impression, read Blink for more) was that she was fine. But I had to check.

Any confusion? No, but really sleepy. She fell asleep in class. Did she leave early? Yes. What did she do at home? She ate and did her homework. Well, that feels better. How about today? Just tired. But she's not confused. Headache? Yes. Worst in your life? No. You've had worse? (I want to be clear). Yes.

On exam, her chin tucks all the way to her chest, smoothly. As her head travels the parabola dictated by her spine in front of me I exhale without knowing I was holding my breath. JAMA, 1999--in the absence of fever, neck stiffness, and altered mental status, an adult is 99% certain or more to not have bacterial meningitis. Go home, you're fine.

On the next afternoon, a fifty year old with a heart attack last year comes in with a cough for a month. Then he mentions palpitations. Then he says when he climbs stairs he gets pain radiating into his left chest that reminds him of his heart attack. Then he says he's sleeping on 5 or 6 pillows at night. Go home? You're fine? Er, no.

Normal ECG, normal chest x-ray doesn't help rule anything out except we're not calling an ambulance. But it's the clinic. So long story short, go home, you're maybe fine...just follow up with cardiology for a stress test. And make sure to come back if things get worse. And please, please, please, follow up. Then he left. That was stressful. That judgement is trickier than trauma.

And my respect for the family practitioner went up. I didn't have the luxury of a chest pain unit, or serial enzymes, or serial ECGs. It was 4:30 on a Friday. I had nothing. I was lucky to get the chest x-ray. Sort the lipids, sort the glucose levels, sort the blood pressures...and don't miss the MI. By the way.

Stressful, when you start to realize that people's lives are, if even for a matter of minutes, in your hands. It's not like 3rd year with residency on the horizon.